Empty an in-use nohup.out file
cat /dev/null >nohup.out
If the file is not in use, the following works in bash
> foo.log
The command above empties out the file foo.log
If sudo is needed, truncate can be used as well
sudo truncate -s 0 foo.log
-s is the size option. 0 in this example sets the size to 0 bytes